Those with vitiligo may experience less skin cancer

How often have you heard the phrase, "Always wear sunscreen!"? Often, right? It's the mantra repeated by dermatologists, plastic surgeons and skincare experts all over the world. Well, in an interesting turn of events, a recent study reported in the New England Journal of Medicine shows that people with vitiligo (a chronic skin problem that removes the pigmentation from patches of their skin) are a bit more immune to skin cancer than the rest of us.

The University of London study involved 4300 men and women, some of whom had vitiligo and some who did not, in an attempt to identify gene patterns to help them know who "might" get vitiligo based on their genetic makeup. What they found were 7 genes connected to vitiligo. There were 2 possible combinations of these 7 genes: one gene pattern for those who had vitiligo and another for those who did not. Oddly, all 4300 tested had one of the two combinations of these 7 genes. Those likely to develop vitiligo had a gene combination that simultaneously decreased their risk of skin cancer, while those with a gene combination that increased their risk of skin cancer also showed a decreased risk of vitiligo.

In laypersons' terms, it means that even if you have the genes most likely to develop vitiligo, that doesn't guarantee that you'll develop it. In fact, only about 1% of the world's population has vitiligo. It just means that you may be more susceptible to getting it--but at the same time, you still have a decreased likelihood of developing skin cancer.

This is important news for those with vitiligo, for whom few treatments really do much good, other than depigmenting the rest of the body to match those areas that have lost pigmentation. Narrow band light has shown to be of some help but other than blister treatments, tattooing and skin grafting, little help is available to most people with this skin disorder.

To your health & beauty,

Dr. Joe Danyo